Disease Registries Development with OMOP/CDM Repository
Our client is an innovative company that has developed a platform for rare disease registries and is building registries and supporting related research in multiple countries. Each registry aggregates data from multiple sources including EHR and other systems.
The internal operational patient data representation is based on the OHDSI OMOP/CDM open source data model. The company has also been developing an extensive technical and content management infrastructure as well as the necessary metadata model and CDM extension in support of its business objectives.
Our client has several teams spread over three continents working internally and with customers.
Engagement Scope and Details
Our client has engaged First Line based on our extensive experience in Healthcare and due to our unique OMOP/CDM expertize.
In support of the client needs we have assemble a multi-functional team that works in close contact with the leadership and the management using agile processes.
As part of this engagement we are working with a wide range of data-related and infrastructure tasks, including:
- Rapid evolution of a multi-tenant cloud-based interactive platform for data collection that supports workflows and logic for clinicians, patients, and researchers
- Building an integration pipeline with Healthcare institutions that utilizes intelligent patient matching, data profiling and data quality functions
- Transformation and mapping of patient data from different EHR systems and legacy data sources to OMOP/CDM
- Data modeling for numerous observational entities of high complexity in support of specific diseases and workflows
- Development of clinical content management tools and infrastructure for collaboration of researchers and clinicians.
Technical Implementation Highlights
- Cloud-based multitenant solution hosted in Microsoft Azure
- Technology stack: Single page architecture, Angular JS, Java Bootstrap, microservices, Microsoft SQL Server Database, Forgerock
- Integration pipeline is based on Intersystems HealthConnect infrastructure
- Intelligent patient matching using open source machine learning software and algorithms
- Persistent storage in OMOP/CDM and extensions; shadow storage for UI is in JSON
- Data conversion from external sources in CCDA, FHIR, HL7, proprietary interfaces and data formats to OMOP/CDM and JSON
About OHDSI OMOP/CDM
OMOP CDM is a Common Data Model open source standard for representation of observational data used for conducting clinical research based on the Real World Evidence (RWE). It is supported and maintained by the OHDSI international community.
The CDM allows users to generate evidence from a wide variety of sources. It has been widely adopted by life sciences companies, healthcare organizations and research communities. It supports collaborative research across data sources around the globe.
OMOP/CDM is also highly extensible and can accommodate extensions and custom entities outside of the standard set.
First Line Expertise in OMOP/CDM
First Line has a team of analysts, Medical Informaticians and engineers with deep expertise in OMOP/CDM who have been mapping and extracting observational data from variety of data sources, modeling complex observational entities, and developing tools and applications around OMOP/CDM for research and analytics.
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For a software vendor like ourselves, picking the right development partner is crucial. First Line’s technical expertise and solid project management, coupled with their proficiency in Agile methodologies, have made them an integral part of our product development group.VP Product Development, leading enterprise software vendor
Our First Line Team has been doing a great job. All of the guys check in great code, and they have a forward thinking mindset, not a feature-to-feature approach. They are also very open in terms of sharing knowledge, which is critical to running productive distributed teams.Application Development Director, global marketing company
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I would like to thank the First Line development team for their dedication and high level of quality in their work. Despite being thousands of miles apart, we have been able to work quickly, effectively, and intelligently. Your team has been a major part of why we have been successful thus far.VP Engineering, e-learning startup
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David Tedford has over 20 years of sales experience within the IT/software industry. He excels at being immersed in a customer's environment, understanding his customers requirements, crafting solutions to meet those requirements, and ultimately providing solutions to his customers.
Senior Vice President
As the head of business development for First Line Software, Vladimir heads up business development in Western Europe and Russia.
Vladimir began his career in IT in 2002, when, as a student of Faculty of Automation of Computer Science of the First Electrotechnical University (ETU “LETI”), he began his work at The Morfizpribor Central Research Institute (CRI). Vladimir joined the StarSoft team (predecessor of First Line Software) in 2004 as a Junior Software Developer. As he gained experience with more and more projects, he was promoted to leadership roles.
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Praha, Czech Republic
UK Business Development
Richard has over 15 years of sales and account management expertise in the IT and Tech sector. He has worked on many outsourcing engagements with global companies.
Gloucestershire, United Kingdom
David is a business development professional with more than 20 years’ experience as a specialist in the acquisition of partnerships and IT/software services for associations, not-for profits and corporations in Australia, New Zealand and USA. He has specific expertise in the healthcare, legal and hospitality industries.